Nearly two years ago, I ran this series on a bunch of reference managers available in both commercial and open source models. Some things have changed since then, and others have not. OpenOffice.org Bibliographic has pretty much stagnated, Bibus has undergone incremental improvements, and Zotero has leap-frogged ahead to a function-rich 2.0 beta and survived a lawsuit from the makers of Endnote (which remains the commercial standard for reference management).
Today, a post at Bora Zivkovic's Blog Around the Clock higlights yet another new bibliographic offering, Mendeley. It is free, but not open source, and still in the beta stage, but it looks like it might offer some interface improvements over programs like Zotero and Endnote. Definitely worth following - do any of you readers have experience with Mendeley?